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My Organizations' Clinical Trials

Showing 200 of 232 entries
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A Study to Evaluate the Efficacy and Safety of Quadruple Therapy (VX-222, Telaprevir,Peginterferon-Alfa-2a, Ribavirin) in Subjects With Chronic Hepatitis C With Compensated Cirrhosis

Phase: N/A Priority: Normal
NCT ID: NCT01516918 Org: User:
Start: 02/29/12 End: 12/31/13 Due: 12/31/14

Rollover Study to Evaluate the Safety and Efficacy of Long-term Treatment With Lumacaftor in Combination With Ivacaftor

Phase: N/A Priority: Normal
NCT ID: NCT02544451 Org: User:
Start: 08/31/15 End: 04/30/20 Due: 04/30/21

A Study to Evaluate the Efficacy and Safety of VX-661 in Combination With Ivacaftor in Subjects Aged 12 Years and Older With Cystic Fibrosis, Heterozygous for the F508del-CFTR Mutation

Phase: N/A Priority: Normal
NCT ID: NCT02516410 Org: User:
Start: 08/31/15 End: 06/07/16 Due: 06/07/17

A Study Evaluating Efficacy and Safety of VX-548 for Acute Pain After an Abdominoplasty

Phase: N/A Priority: Normal
NCT ID: NCT05034952 Org: User:
Start: 08/30/21 End: 12/21/21 Due: 12/21/22

A Study Evaluating the Long Term Safety and Efficacy of VX-659 Combination Therapy

Phase: N/A Priority: Normal
NCT ID: NCT03447262 Org: User:
Start: 07/13/18 End: 09/09/20 Due: 09/09/21

Evaluation of Long-term Safety and Efficacy of ELX/TEZ/IVA TC Combination Therapy in Participants With Cystic Fibrosis Who Are 6 Years of Age and Older

Phase: N/A Priority: Normal
NCT ID: NCT04183790 Org: User:
Start: 02/17/20 End: 02/24/24 Due: 02/24/25

A Phase 2/3 Open-label Extension Study to Evaluate Long-Term Safety and Efficacy With VX-509 in Subjects With Rheumatoid Arthritis

Phase: N/A Priority: Normal
NCT ID: NCT01830985 Org: User:
Start: 04/30/13 End: 07/31/14 Due: 07/31/15

A Safety and Efficacy Study Evaluating CTX001 in Subjects With Severe Sickle Cell Disease

Phase: N/A Priority: Normal
NCT ID: NCT03745287 Org: User:
Start: 11/27/18 End: 07/31/25 Due: 07/31/26

Evaluation of the Efficacy and Safety of VX-864 in Subjects With the PiZZ Genotype

Phase: N/A Priority: Normal
NCT ID: NCT04474197 Org: User:
Start: 07/24/20 End: 05/04/21 Due: 05/04/22

A Phase 1 Dose Escalation Study of VX-993 in Healthy Participants

Phase: N/A Priority: Normal
NCT ID: NCT05653323 Org: User:
Start: 12/14/22 End: 09/12/23 Due: 09/12/24

Study to Evaluate Elexacaftor/Tezacaftor/Ivacaftor (ELX/TEZ/IVA) Long-term Safety and Efficacy in Subjects Without F508del

Phase: N/A Priority: Normal
NCT ID: NCT05331183 Org: User:
Start: 11/23/22 End: 04/06/27 Due: 04/06/28

A Study to Evaluate the Effect of VX-661 in Combination With Ivacaftor on Chest Imaging Endpoints in Subjects With Cystic Fibrosis, Homozygous for the F508del CFTR Mutation

Phase: N/A Priority: Normal
NCT ID: NCT02730208 Org: User:
Start: 09/30/16 End: 07/31/18 Due: 07/31/19

A Study to Confirm the Long-term Safety and Effectiveness of Kalydeco in Patients With Cystic Fibrosis Who Have an R117H-CFTR Mutation, Including Pediatric Patients

Phase: N/A Priority: Normal
NCT ID: NCT02722057 Org: User:
Start: 12/31/15 End: 12/31/19 Due: 12/31/20

A Study to Investigate VX-787 Given to Adult Volunteers Inoculated With Live Influenza Virus

Phase: N/A Priority: Normal
NCT ID: NCT01561807 Org: User:
Start: 03/31/12 End: - Due: -

Evaluation of the Effect of Suzetrigine (SUZ) on the Pharmacokinetics of Oral Contraceptives in Healthy Female Participants

Phase: N/A Priority: Normal
NCT ID: NCT06820307 Org: User:
Start: 02/25/25 End: 04/29/25 Due: 04/29/26

Study to Assess the Efficacy and Safety of VX-210 in Subjects With Acute Traumatic Cervical Spinal Cord Injury

Phase: N/A Priority: Normal
NCT ID: NCT02669849 Org: User:
Start: 07/31/16 End: 11/30/18 Due: 11/30/19

An Open-Label Study of the Effect of Telaprevir in Combination With Peginterferon Alfa-2b and Ribavirin in Pediatric Subjects Infected With Hepatitis C Virus

Phase: N/A Priority: Normal
NCT ID: NCT01701063 Org: User:
Start: 01/31/13 End: 04/30/15 Due: 04/30/16

Study of VX-121 in Healthy Subjects and in Subjects With Cystic Fibrosis

Phase: N/A Priority: Normal
NCT ID: NCT03768089 Org: User:
Start: 03/20/18 End: 05/03/19 Due: 05/03/20

Evaluation of the Pharmacokinetic Drug-drug Interactions Between VX-993 and Metformin in Healthy Adults

Phase: N/A Priority: Normal
NCT ID: NCT06523595 Org: User:
Start: 07/31/24 End: 12/31/24 Due: 12/31/25

A Phase I Trial of AVN944, an IMPDH Inhibitor, in Adults With Advanced Stage Solid Tumors

Phase: N/A Priority: Normal
NCT ID: NCT00923728 Org: User:
Start: 04/30/09 End: 03/31/10 Due: 03/31/11

A Rollover Study for Subjects Participating in the Control Arm of Study VX06-950-106, VX05-950-104 and VX05-950-104EU Whose Plasma Hepatitis C Virus (HCV) Ribonucleic Acid (RNA) Levels Did Not Respond to Therapy

Phase: N/A Priority: Normal
NCT ID: NCT00535847 Org: User:
Start: 10/31/07 End: 02/28/10 Due: 02/28/11

Study of the Effect of Ivacaftor on Lung Clearance Index in Subjects With Cystic Fibrosis and the G551D Mutation

Phase: N/A Priority: Normal
NCT ID: NCT01262352 Org: User:
Start: 01/31/11 End: 11/30/11 Due: 11/30/12

A Study Evaluating the Safety and Efficacy of VX-659 Combination Therapy in Subjects With Cystic Fibrosis

Phase: N/A Priority: Normal
NCT ID: NCT03224351 Org: User:
Start: 08/08/17 End: 02/28/18 Due: 02/28/19

A Study to Evaluate Efficacy and Safety of VX-150 in Subjects With Acute Pain Following Bunionectomy

Phase: N/A Priority: Normal
NCT ID: NCT03206749 Org: User:
Start: 06/29/17 End: 12/08/17 Due: 12/08/18

A Phase 2 Study to Evaluate Effects of VX-661/Ivacaftor on Lung and Extrapulmonary Systems in Subjects With Cystic Fibrosis, Homozygous for the F508del-CFTR Mutation

Phase: N/A Priority: Normal
NCT ID: NCT02508207 Org: User:
Start: 02/29/16 End: 06/30/17 Due: 06/30/18